Monotherapy Of Hypertension

Monotherapy:

(i). Standard initial monotherapy preferences.
(a). Diuretics such as Hydrochlorothiazide.
* Secondly used diuretic if not possible first.
* Excellent adjunct to other antihypertensives.
* Lisinopril and Amlodipine are less effective so they are better.
*Decrease risk of Cardio vascular arythemia , Myocardial Infarction, Congestive heart failure comparitive to other agents.

(b). Beta Blocker (Propanalol, Atenol etc)
(c). Angiotensin Converting Enzyme Inhibitor (ACE)
(c). Angiotensin Receptor Blocker (ARP)

(ii). Reasons compiling for other antihypertensive
(a). AntiHypertensives for Specific Comorbid Diseases
(b). Antihypertensives for Specific Populations

(iii). Avoid the following agents for monotherapy.
(a). Alpha blockers
(b). Hydralazine
(c). Minoxidil
(d). Calcium Channel Blockers

(iv). Avoid in low compliant patients bcoz of rebound Hypertension.
(a). Beta Blockers
(b). Clonidine